EOSIN Y

EOSIN Y - Names and Identifiers

Name	2,4,5-7-Tetrabromofluorescein disodium salt
Synonyms	EOSIN Eosine Eosin Y Bromo B bromo ts Eosin ys bromo xx bromo fl eosine g AKA230(2) bromo jps waterred2 bromo 4dc 11445 red 11731 red AKA230(1) eosine yy Eosine YS C.I. 45380 Eosine YSK bromo acid eosine bpc RED 21 LAKE Acid red 87 Bromoeosine bromo x-100 bronze bromo Sodium eosine Eosin Disodium Disodium eosin eosin disodium aizen eoxine gh sodium eosinate certiqual eosine fenazo eosine xg C.I. Acid Red 87 Bromo fluorescein Acid Red 87 (C.I.) Eosin Y Sodium Salt hidacid white bromo symuler eosin toner phloxine red 20-7600 Eosine yellowish-(YS) hidacid boiling bromo Bromofluoresceic acid irgalite bronze red cl Acid Red 87~C.I. 45380 hidacid eosine soda salt EOSIN Y, INDICATOR GRADE 2,4,5,7-Tetrabromofluorescein Tetrabromofluorescein Sodium Salt 2,4,5,7-tetrabromo-3,6-fluorandiol Eosin Y, high purity biological stain 2,4,5-7-Tetrabromofluorescein disodium salt 2,4,5,7-Tetrabromofluorescein (Sodium salt) 2',4',5',7'-tetrabromofluorescein disodium salt disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoate disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate 9-(o-Carboxyphenyl)-2,4,5,7-tetrabromo-3,6-dihydroxyxanthene, sodium salt 2,4,5,7-tetrabromo-9-o-carboxyphenyl-6-hydroxy-3-isoxanthone, disodium salt 2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthene-9-yl)benzoic acid, disodium salt 2,4,5,7-Tetrabromo-3,6-dihydroxyxanthene-9-spiro-1'-3H-isobenzofuran-3'-one disodium salt 2,4,5,7-Tetrabromo-3,6-dihydroxyxanthene-9-spiro-1'-3H-isobenzofuran-3'-one dipotassium salt 2',4',5',7'-Tetrabromo-3',6'-dihydroxy-spiro[3H-isobenzofuran-1,9'-xanthen]-3-one disodium salt 2',4',5',7'-Tetrabromo-3',6'-dihydroxy-spiro[3H-isobenzofuran-1,9'-xanthen]-3-one dipotassium salt Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',4',5',7'-tetrabromo-3',6'-dihydroxy-,disodium salt(?)
CAS	548-26-5 17372-87-1
EINECS	241-409-6
InChI	InChI=1/C20H8Br4O5.3Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;;/h1-6,25H,(H,27,28);;;/q;3*+1/p-2

EOSIN Y - Physico-chemical Properties

Molecular Formula	C20H6Br4Na2O5
Molar Mass	691.85418
Density	1.02g/mLat 20°C
Melting Point	>300°C
Boling Point	682.3℃ at 760mmHg
Flash Point	11°C
Water Solubility	freely soluble
Solubility	Soluble in water, fairly soluble in alcohol, insoluble in ether
Appearance	Red with blue crystal or brown powder
Color	Reddish
Maximum wavelength(λmax)	514nm
Merck	14,3603
BRN	3586809
pKa	2.9, 4.5(at 25℃)
PH	9.2 (10g/l, H2O, 20℃)
Storage Condition	Store at RT.
Stability	Stable. Incompatible with strong oxidizing agents.
Sensitive	Easily absorbing moisture
MDL	MFCD00133309
Use	Used as adsorption indicator, etc

EOSIN Y - Risk and Safety

Risk Codes	R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 - R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed R36 - Irritating to the eyes R10 - Flammable
Safety Description	S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S39 - Wear eye / face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN 1230 3/PG 2
WGK Germany	1
RTECS	LM5850000
TSCA	Yes
HS Code	32041200
Toxicity	LD50 orally in Rabbit: > 2000 mg/kg

EOSIN Y - Reference

Reference

1. Zhang Liwei, Kang Jingjing, Li Yueqin, etc. Histopathological changes of canine uterus with pyometra [J]. Heilongjiang Journal of Animal Husbandry and Veterinary Medicine (second half month), 2020, 000(002):70-71,148-149.
2. Huang Chunyang, si Lifang, di lan, et al. Effects of octylphenol on the development and histological structure of epididymis, seminal vesicle and prostate in mice [J]. Progress in Animal Medicine, 2013, 29 (02):48-51.
3. Fang Xin, Li hailing, Hu Yueling, etc. Mechanism of kidney damage and oxidative stress induced by Di (2-ethylhexyl) phthalate in mice [J]. Chinese Journal of Preventive Medicine, 2014.
4. Jin Zhuhao, Cui Yunqiu, Sun Jingxin, Jin Guangyu, whole Jishan. Preparation and evaluation of liposomes loaded with magnetic iron oxide nanoparticles [J]. Journal of Yanbian University (Natural Science Edition), 2020,46(04):326-332.
5. Jayachandran, Muthukumaran, et al. "Isoquercitin ameriorates hyperglycomia and regulatory key enzymes of glucose metabolism via insulin signaling pathway in streptozotocin-induced diabetic rats." European journal of pharmacology 829 (2018): 112-120.https://
6. [IF=4.432] Muthukumaran Jayachandran et al."Isoquercetin ameliorates hyperglycemia and regulates key enzymes of glucose metabolism via insulin signaling pathway in streptozotocin-induced diabetic rats."Eur J Pharmacol. 2018 Jun;829:112
7. [IF=3.407] Ya-Ping Jiang et al."Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage."Chem-Biol Interact. 2020 Jan;315:108869
8. [IF=4.379] Gong Gu et al."Salivary protein 7 of the brown planthopper functions as an effector for mediating tricin metabolism in rice plants."Sci Rep-Uk. 2022 Feb;12(1):1-13

EOSIN Y - Introduction

& & Eosin Y is a xanthogen dye used for differential staining of connective tissue and cytoplasm. In histopathology, it is used as a regaining agent after hematoxylin and before methylene blue. It is also used as a background stain in contrast to a nuclear stain. Eosin Y disodium salt has been used to determine sperm motility. The swollen and stained sperm is thought to have died. In the corneal epithelium, it has been used in the process of immunostaining.

Last Update：2022-10-16 17:26:13

EOSIN Y - Reference Information

overview	water-soluble eosin Y is a chemically synthesized acid dye that dissociates into negatively charged anions in water and binds with positive amino cations of proteins to stain the cytoplasm, cytoplasm, red blood cells, muscle, connective tissue, eosinophilic granules, etc. are stained to varying degrees of red or pink, in sharp contrast to the blue nucleus.
application	eosin is a good dye for cytoplasm. It is generally used with hematoxylin or other dyes such as Meilan.
use	Eosin Y is an acid dye that dyes the cytoplasm pink (eosinophilic). It is one of the commonly used dyeing reagents in tissue and cytochemistry. It is often used with hematoxylin (a basic dye, the nuclei are dyed purple-blue (basophilic)) and used in combination (HE staining method). In immunohistochemical experiments, it is often used as a lining reagent to facilitate the observation of tissue and cell structure. Used as adsorption indicator, etc. Biochemical research Used as a biological stain. It is also used as an adsorption indicator for precipitation titration to determine Br-, I-, SCN-, MoO, Ag, etc. Used as a developer for the determination of Ag +, Pb2 +, Mn2 +, Zn2 +, etc. biological staining agent, peptide, protein, protoplasm, alkaline phosphatase, etc. Photometric determination of silver (sub-micrograms); Wright stain component, used to detect blood cells; Adsorption indicator, titrating bromine, iodine, fluorine plasma
category	toxic substances
toxicity classification	poisoning
acute toxicity	abdominal cavity-rat LDL0: 500 mg/kg; Oral-mouse LD50: 2344 mg/kg
flammability hazard characteristics	thermal decomposition to discharge toxic sodium oxide and bromide smoke
storage and transportation characteristics	warehouse ventilation and low temperature drying
extinguishing agent	water, dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent
color index	45380
biological field application	Treating age-related macular degeneration,burns,cancer,diabetes,obesity,dental bone defects,gastroesophageal reflux disease,prostate cancer,viral diseases; stents; wound-healing materials
EPA chemical information	information provided by: ofmpub.epa.gov (external link)

Last Update：2024-04-09 01:59:59

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View History

EOSIN Y
C.I. Acid Red 151
CANOLA
Disperse Red 58
毒重石

EOSIN Y

2,4,5-7-Tetrabromofluorescein disodium salt

CAS: 548-26-5;17372-87-1

Molecular Formula: C20H6Br4Na2O5

EOSIN Y - Names and Identifiers

EOSIN Y - Physico-chemical Properties

EOSIN Y - Risk and Safety

EOSIN Y - Reference

EOSIN Y - Introduction

EOSIN Y - Reference Information

Supplier List

EOSIN Y Request for Quotation

2,4,5-7-Tetrabromofluorescein disodium salt

CAS: 548-26-5;17372-87-1

Molecular Formula: C20H6Br4Na2O5

EOSIN Y - Names and Identifiers

EOSIN Y - Physico-chemical Properties

EOSIN Y - Risk and Safety

EOSIN Y - Reference

EOSIN Y - Introduction

EOSIN Y - Reference Information

Supplier List

EOSIN Y